Guest lecture by prof. Onur Mutlu from the ETH University, Zurich, and Carnegie Mellon University (USA)




Guest lecture by prof. Onur Mutlu from the ETH University, Zurich, and Carnegie Mellon University (USA)

Prof. Onur Mutlu, distinguished professor at Carnegie Mellon (USA) and ETH Zurich (CH) Universities, the first most cited scientist in the field of memory systems, and the third most cited scientist in the field of genomic analysis (Google Scholar), will hold a series of lectures at the University of Montenegro. Only in the year 2022 his research results earned over 6300 Google Scholar citations.

On Friday, June 9th, at 4 p.m., in the amphitheater of the Faculty of Medicine of the University of Montenegro, he will hold a lecture on the topic: "Accelerating Genome Analysis".

Abstract

Genome analysis is the foundation of many scientific and medical discoveries as well as a key pillar of personalized medicine. Any analysis of a genome fundamentally starts with the reconstruction of the genome from its sequenced fragments. This process is called read mapping. One key goal of read mapping is to find the variations that are present between the sequenced genome and reference genome(s) and to tolerate the errors introduced by the genome sequencing process. Read mapping is currently a major bottleneck in the entire genome analysis pipeline because state-of-the-art genome sequencing technologies are able to sequence a genome much faster than the computational techniques that are employed to reconstruct the genome. New sequencing technologies, like nanopore sequencing, greatly exacerbate this problem while at the same time making genome sequencing much less costly.

This talk describes our ongoing journey in greatly improving the performance of genome analysis (with a focus on read mapping and beyond). We show that significant improvements are possible with both algorithmic and hardware-based approaches and their combination. We conclude with a foreshadowing of future challenges brought about by very low-cost new sequencing technologies and their potential use cases in public health, science, and medicine.

Short bio

Onur Mutlu (http://people.inf.ethz.ch/omutlu/) is a Professor of Computer Science at ETH Zurich, as well as at Carnegie Mellon University, where he held the Strecker Early Career Professorship. His current broader research interests are computer architecture, systems, hardware security and bioinformatics. His team, with collaborators, invented a number of industry-impacting techniques used in commercial microprocessors and memory and storage devices. He obtained his PhD and MS in Electronic and Computer Engineering from the University of Texas at Austin, while his BSc in Computer Engineering and Psychology was completed at the University of Michigan, Ann Arbor. He started the Computer Architecture group at Microsoft Research (2006-2009) and held various positions in production and research departments at Intel Corporation, Advanced Micro Devices, VMware and Google. He received a large number of awards, among which the following stand out: Huawei OlympusMons Award for Storage System Research, Google Security and Privacy Research Award, Intel Outstanding Researcher Award, IEEE High Performance Computer Architecture Test of Time Award, NVMW Persistent Impact Award, the IEEE Computer Society Edward J. McCluskey Technical Achievement Award, ACM SIGARCH Maurice Wilkes Award, inaugural IEEE Computer Society Young Computer Architect Award, inaugural Intel Early Career Faculty Award, US National Science Foundation CAREER Award, Carnegie Mellon University Ladd Research Award, as well as awards for academic partnership by various companies.

Prof. Mutlu is an ACM Fellow "for contribution to research in the field of computer architecture, especially in memory systems", an IEEE Fellow for "contribution to research and practice in the field of computer architecture", as well as a member of the European Academy (Academia Europea). His lectures and materials in the field of computer architecture and digital logic design are freely available on the YouTube channel (https://www.youtube.com/OnurMutluLectures). Also, a large number of software and hardware artifacts of his research group are freely available online (https://safari.ethz.ch/). For more information, you can visit his webpage at https://people.inf.ethz.ch/omutlu/), while you can find Prof. Mutlu’s CV at the following address: https://people.inf.ethz.ch/omutlu/doc/onur_cv.pdf.  

All those interested are requested to confirm their attendance at the lecture by sending an email to the following address: masaz@ucg.ac.me.



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