FARMAKOLOGIJA SA TOKSIKOLOGIJOM

After finishing one semester of study and passing an examination in Pharmacology with toxicology, medical students should have the following outcomes: 1. Define and explain the mechanisms of action of certain drug groups and relate them to their pharmacological effects. 2. Describe the fate of a drug in the human body (absorption, distribution, metabolism, excretion) and define the most important pharmacokinetic parameters. 3. Describe the most important pharmacokinetic properties of individual groups of drugs and compare the pharmacokinetic specifities of some drugs within the group that are of importance for their application. 4. Connect indications and contraindications for the use of drug to its pharmacological effects. 5. Anticipate and recognize side effects of drugs and drug interactions that result from their pharmacokinetic, pharmacodynamic and physicochemical properties. 6. Recognize the symptoms of the most common acute poisonings with drugs and other substances (heavy metals, poisons that pollute the human environment, etc.) and define the principles of treatment. 7. Prescribe the optimal medication within the appropriate pharmacotherapeutic groups and for a given indication, compare pharmaceutical forms of individual drugs and define the capabilities and limitations of their application.