BIOLOGIJA SA HUMANOM GENETIKOM

After completing a semester of instruction and passing the exam in the subject of Human Genetics, a medical student will be able to: 1. Describe the structure and function of the human genetic basis, including nucleic acids, replication mechanisms, translation and transcription, basic enzyme regulatory systems, the genetic code, chromosome organization, gene expression control, and the genetic basis of reproduction. 2. Define the mechanisms of mutation formation and their impact on human health, as well as the mechanisms of repairing errors in hereditary material. 3. Define the rules of inheritance and describe various groups of inherited diseases (chromosomal, monogenic, polygenic) and their impact on human health and offspring. 4. Define basic cytogenetic cell culture methods, karyotype preparation, and analyze the human karyotype using a light microscope. 5. Describe basic molecular genetics methods, including DNA isolation, PCR, endonuclease restriction, and gel electrophoresis. 6. Describe the application of modern cytogenetic and molecular-genetic techniques in the diagnosis and treatment of inherited disorders. 7. Demonstrate a high level of expertise in using relevant literature, websites, and databases for Human Genetics research and utilizing these sources to evaluate, develop, and test hypotheses in the field of Human Genetics.